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Sinemet (Carbidopa, Levodopa)Carbidopa and Levodopa (trade names include Sinemet; Apo-Levocarb; Co-Careldopa; Sinemet-CR; Dopadura-C; Dopicar; Sinemet-LP; Duodopa; Half Sinemet; Kardopal; Levocarb; Sinemet Plus; Levodopa Comp.; Syndopa; Levomed; Nacom; Nakom; Sinemet Retard; Syndopa Plus; Tidomet) is a combined antiparkinson drug from dopa derivatives (Levodopa) and decarboxylase inhibitors (Carbidopa) pharmacological groups. This medication is used for the treatment of Parkinson's disease and its symptoms and conditions, including postencephalitic parkinsonism, idiopathic Parkinson's disease, symptomatic parkinsonism, muscle stiffness, tremors, spasms, and poor muscle control. It is also prescribed to treat Parkinson symptoms caused by carbon monoxide poisoning or manganese intoxication. Symptoms of Parkinson's disease may be caused by low levels of chemical called dopamine in the brain. Levodopa works by converting to dopamine in the brain. Carbidopa helps prevent the breakdown of levodopa before it can reach the brain and take effect.

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Pharmaceutical forms and dosages:
  • Sinemet (Carbidopa, Levodopa) 10/100 mg tablets
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  • Levodopa, Carbidopa (Sinemet generic) 25/100 mg tablets
  • Levodopa, Carbidopa (Sinemet generic) 50/250 mg tablets
  • Quantity in a package:
  • 30, 60, 90 pills
  • 30, 60, 90, 120, 180, 360 pills
  • 30, 60, 90, 120, 180, 360 pills
  • 30, 60, 90 pills
  • Type of Carbidopa plus Levodopa - brand / generic:
  • Sinemet (Carbidopa, Levodopa) generic
  • Carbidopa and Levodopa (Sinemet) generic
  • Sinemet generic
  • LCD brand
  • Syndopa brand
  • Levodopa, Carbidopa (Sinemet) generic
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    Recent posts:

  • Carbidopa, Levodopa medications
  • Carbidopa, Levodopa combinations


    There is an additional general information about Carbidopa / Levodopa (Sinemet):


    Medical and pharmaceutical categories for levodopa plus carbidopa:

  • Antiparkinsonian drugs
  • Dopamine precursors
  • Central nervous system agents


    The Anatomical Therapeutic Chemical (ATC) classification system carbidopa with levodopa codes:

  • N - Nervous system
  • N04 - Anti-Parkinson drugs
  • N04B - Dopaminergic agents
  • N04BA - Dopa and dopa derivatives
  • N04BA02 - Levodopa and decarboxylase inhibitor


    Levodopa and Carbidopa in The International Statistical Classification of Diseases and Related Health Problems (ICD-10, World Health Organization) codes:

  • Parkinson's disease - G20
  • Secondary parkinsonism - G21
  • Parkinsonism in diseases classified elsewhere - G22


    Pregnancy categories for Carbidopa, Levodopa (Sinemet):

  • B3 - Australia
  • C - United States (Risk cannot be ruled out)


    Salts and other levodopa with carbidopa forms used as active pharmaceutical ingredients (API):

  • Carbidopa Base with Levodopa Base
  • Carbidopa Anhydrous with Levodopa Base
  • Carbidopa Monohydrate with Levodopa Base


    Synonyms of carbidopa and levodopa, international and chemical names:

  • Carbidopum
  • Hadrazino-Alpha-Methyldopa
  • L-Alpha-Methyldopahydrazine
  • N-Aminomethyldopa
  • S(-)-Carbidopa

  • (-)-Dopa
  • 3-Hydroxy-L-Tyrosine
  • 3-Hydroxytyrosine
  • Dihydroxy-L-Phenylalanine
  • L-(-)-Dopa
  • L-Beta-(3,4-Dihydroxyphenyl)alanine
  • L-Dopa
  • Levedopa
  • Levodopum
  • L-O-Hydroxytyrosine
  • Tyrosine, 3-Hydroxy-

  • Levocarb
  • Co-Careldopa


    Best known carbidopa with levodopa brands, generics and trade names in various countries:

  • Apo-Levocarb - Apotex; Hind Wing; Pharmaforte
  • Atamet - Elan Pharmaceuticals
  • Carbidopa; Levodopa - Accord Healthcare; Actavis; Hexal; Mylan; Ratiopharm; Sandoz; Sun Pharmaceutical Industries; Teva; Watson Pharmaceuticals
  • Carbidopa; Levodopa CR - Sandoz
  • Carbilev - Ranbaxy; Aspen
  • Co-Careldopa - Teva
  • Credanil - Remedica; Goldplus Universal
  • Cronomet - Merck
  • Dopadura-C - Merck
  • Dopicar - Teva; Merck
  • Duodopa - Solvay; Abbott; AbbVie; Neopharma, Sweden; Zuellig Pharma
  • Half Sinemet - Bristol-Myers Squibb; United Drug
  • Kardopal - Orion Pharma
  • LCD - Intas Pharmaceuticals
  • Lebocar - Pfizer
  • Levobeta C - Betapharm Arzneimittel
  • Levocar - Sandoz
  • Levocarb - Teva; Biolab Sanus Farmaceutica
  • Levocarb CR - AA Pharma
  • Levocomp - Hexal
  • Levodopa Comp. - CT-Arzneimittel; Ratiopharm
  • Levodopa Comp. C - Stada
  • Levomed - Medochemie; Komedic; Medline; Star Medical Supplies
  • Nacom - Bristol-Myers Squibb
  • Nacom Retard - Bristol-Myers Squibb
  • Nakom - Sandoz; Lek; Merck
  • Nakom Mite - Sandoz
  • Parcopa - Schwarz Pharma
  • Parkidopa - Cristalia Produtos Quimicos Farmaceuticos
  • Parkinel - Bago Laboratorios
  • Sinemet - Bristol-Myers Squibb; M & H Manufacturing; Merck; Mylan; United Drug; Vianex
  • Sinemet-CR - Bristol-Myers Squibb; DKSH; Four Star; Institute of Pharmaceutical Research and Technology; Invida; Merck; Mylan; Zuellig Pharma
  • Sinemet-LP - Bristol-Myers Squibb; Merck
  • Sinemet Plus - Bristol-Myers Squibb
  • Sinemet Retard - Bristol-Myers Squibb; Merck
  • Syndopa - Sun Pharmaceutical Industries; Pharmaland 1982
  • Syndopa CR - Sun Pharmaceutical Industries; Pharmaland 1982
  • Syndopa Plus - Sun Pharmaceutical Industries
  • Tidomet - Torrent Pharmaceuticals; Kaspa Pharmaceutical Thailand; Metro Drug Distribution


    Some other medications in Sinemet (Carbidopa; Levodopa) pharmacological classes:

  • Almirid (Dihydroergocryptine Mesylate)
  • APO-Go (Apomorphine)
  • Aricept (Donepezil)
  • Artane (Trihexyphenidyl)
  • Dopergin (Lisuride)
  • Dostinex (Cabergoline)
  • Eldepryl (Selegiline)
  • Ethylevodopa (Etilevodopa)
  • Exelon (Rivastigimine)
  • Glucophage (Metformin)
  • Kemadrin (Procyclidine)
  • Levomet (Melevodopa)
  • Liserdol (Metergoline)
  • Mirapex (Pramipexole)
  • Namenda (Memantine)
  • Neupro (Rotigotine)
  • Norprolac (Quinagolide)
  • Parlodel (Bromocriptine)
  • Permax (Pergolide)
  • Reminyl (Galantamine)
  • Requip (Ropinirole)
  • Stalevo (Carbidopa; Levodopa; Entacapone)
  • Symmetrel (Amantadine)
  • Teluron (Terguride)
  • Trivastal (Piribedil)


    Here is a list of some medications containing "Carbidopa" and "Levodopa" as main active pharmaceutical ingredients (APIs) of carbidopa / levodopa drugs, their trade names, available forms, doses and also pharmaceutical companies - manufacturers, distributors and suppliers, researchers and developers:

    Trade name of the drug Pharmaceutical forms and doses Companies
    Co-Careldopa
  • Tablets; Oral; Carbidopa 25 mg; Levodopa 100 mg
  • Tablets; Oral; Carbidopa 25 mg; Levodopa 250 mg
  • Teva
  • Levocarb
  • Tablets; Oral; Carbidopa 25 mg; Levodopa 250 mg
  • Tablets; Oral; Carbidopa 50 mg; Levodopa 200 mg
  • Teva
  • Biolab Sanus Farmaceutica
  • Sinemet
  • Tablets; Oral; Carbidopa 10 mg; Levodopa 100 mg
  • Tablets; Oral; Carbidopa 25 mg; Levodopa 100 mg
  • Tablets; Oral; Carbidopa 25 mg; Levodopa 250 mg
  • Tablets, Prolonged Release; Oral; Carbidopa 100 mg; Levodopa 25 mg
  • Tablets, Prolonged Release; Oral; Carbidopa 200 mg; Levodopa 50 mg
  • Bristol-Myers Squibb
  • Chandra Bhagat Pharma
  • DKSH
  • Four Star
  • Invida
  • M & H Manufacturing
  • Merck
  • Mylan
  • United Drug
  • Vianex
  • Zuellig Pharma
  • Sinemet Plus
  • Tablets; Oral; Carbidopa 25 mg; Levodopa 100 mg
  • Bristol-Myers Squibb
  • Syndopa
  • Tablets, Controlled Release; Oral; Carbidopa 50 mg; Levodopa 200 mg
  • Tablets; Oral; Carbidopa 10 mg; Levodopa 100 mg
  • Tablets; Oral; Carbidopa 25 mg; Levodopa 250 mg
  • Sun Pharmaceutical Industries
  • Pharmaland 1982


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